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The DNAnexus Diagnostics Production Scaler

Replace brittle, do-it-yourself bioinformatics with a production-grade operating system purpose-built for commercial diagnostics—turning your sample-to-report workflow into a scalable, reliable software factory.

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The Need

In high-volume molecular diagnostics, success is defined by one metric: turnaround time delivered at scale—without sacrificing margin. As test volumes spike and assay complexity grows, fragile homegrown pipelines become a critical liability. Failed runs, re-processing, and SLA penalties quietly erode profitability and patient trust.

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Use Case

Scaling Liquid Biopsy at Volume

A commercial diagnostics provider running high-volume liquid biopsy testing experiences frequent pipeline failures during demand spikes—driving re-runs, missed SLAs, and margin erosion.

By deploying the Diagnostics Production Scaler, the lab standardizes execution across assays, automates failure recovery, and centralizes analysis across regions. The result is predictable turnaround time, fewer re-runs, and a materially lower cost per test—without expanding the team.

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Our Solution

The DNAnexus Diagnostics Production Scaler is a production-grade, CAP/CLIA-aligned platform designed to automate the full lifecycle of a clinical test—from R&D validation through high-throughput commercial operations.

Rather than stitching together cloud services and scripts, diagnostics teams gain a hardened execution layer that delivers reliability, speed, and cost control by design.

  • Fault-Tolerant Execution Engine: Automatic retry and failover logic ensures pipelines complete successfully—without manual intervention.

  • Smart Reuse Technology: Detects completed pipeline steps and skips redundant computation, reducing runtime and cloud costs by 40–80%*.

  • Global Centralization Model: Sequence locally, analyze centrally—protecting intellectual property while operating across multiple regions.

  • Immutable QC & Provenance: Every sample, parameter, and result is fully traceable and reproducible—even years later.

  • Production-Ready Compliance Foundation: Built to support CAP/CLIA validation, audits, and inspection readiness as volume scales.

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Interested in learning more about The Diagnostics Production Scaler?

Your Key Benefits and Outcomes

  • Reliability at Production Scale: Eliminate pipeline failures during volume spikes with automated retry logic and fault-tolerant execution.

  • Lower Cost-per-Sample: Reduce re-runs and optimize cloud economics through intelligent reuse and automated infrastructure management.

  • Faster Time to Market: Validate, launch, and scale new assays dramatically faster without rebuilding pipelines or hiring additional staff.

Why DNAnexus?

DNAnexus operates some of the most demanding genomic production environments in the industry. The Diagnostics Production Scaler distills that experience into a hardened platform trusted by leading diagnostics organizations to deliver results at scale—without compromising reliability, compliance, or margins.

We can help you achieve your goals. Start the process with a brief scientific consultation to determine how we can help.