Resource Center
Welcome to the repository for all things DNAnexus. Sort through case studies, webinars, white papers, and videos by their associated DNAnexus product and key topics for a deeper dive into the power of our platform and expertise.
Featured
White Paper
New
The Total Economic Impact Of The DNAnexus Platform
Cost Savings And Business Benefits
Enabled By The DNAnexus Platform
A FORRESTER TOTAL ECONOMIC IMPACT STUDY
MAY 2023
Case Study
New
How DNAnexus offers better ROI than DIY solutions
DNAnexus, a cloud-based precision health data management and analysis platform, offers several advantages over DIY solutions.
White Paper
New
Overcome the four common data challenges in clinical diagnostics
How clinical diagnostic labs can flexibly scale to meet the demand for increased NGS test volume.
Case Study
New
Standardizing portable, reproducible analysis pipelines: Pharma Experience
Learn how Eli Lilly partnered with DNAnexus and used open-source standards to tackle the changing bioinformatics landscape with on-demand compute and portable, reproducible pipelines to run in any region.
White Paper
When to Build vs.
Buy an Enterprise
Genomics Platform?
Your team members contribute the most when they’re focused on science, not when they’re spending valuable time fixing and optimizing your bioinformatics system.
White Paper
4Strategies to Accelerate Precision Drug Discovery
Large-scale omics datasets are revolutionizing how pharmaceutical companies identify targets for therapeutic development, and have become one of the main paths in accelerating precision medicine.
Case Study
Ultragenyx: Overcoming Technological Challenges to Fast-Track R&D
Advancing Rare Disease Therapeutics with DNAnexus Titan™
Ultragenyx chose to implement DNAnexus Titan™, a unified NGS analysis platform, to bring data and pipelines together in one secure environment for streamlined multi-omics data analysis.
White Paper
Build or Buy?
6Questions to Consider When Investigating NGS Informatics Solutions
A bioinformatics solution is the backbone of any successful precision medicine initiative.
Case Study
Comprehensive Genome Assemblies Made Simple
Featured Partner:

Discover the Difference
De novo genome assembly is a complex task made more challenging by high levels of genetic diversity, repetitive elements, and duplicated genomic regions.
White Paper
Working with
UK Biobank Data
A Research Guide
Do you have the right informatics strategy to get to insights quickly while working with the UK Biobank (UKB) dataset?
Case Study
Rapid Whole-Genome Sequencing Decreases Infant Morbidity and Cost of Hospitalization
rWGS is a unique, high-cost healthcare innovation that appears to improve healthcare outcomes while decreasing cost of care.
Video
UKB RAP CLI Series 3: Searching for Files Using dx find
Best practices for how to sort for and find your data via the CLI on the UK Biobank Research Analysis Platform

Video
UKB RAP CLI Series 1: Introduction to Command Line Interface (CLI)
Gain an understanding of the Command Line Interface on the UK Biobank Research Analysis Platform and how you can use it to perform all of your work on the Platform.

Video
Large-Scale Sequencing at Regeneron Genetics Center
Jeffrey Reid, PhD, Executive Director of Genome Informatics at Regeneron presents lessons learned from largescale sequencing in the cloud with Regeneron Genetics Center.

Blog
DNAnexus Detectives: Using Amazon Web Services to Help Solve a Medical Mystery
Video
How to Use RStudio on the UK Biobank Research Analysis Platform
UK Biobank researchers can now access RStudio as a trial version on the DNAnexus-powered Research Analysis Platform. This tutorial covers how to launch RStudio Workbench, using RStudio and working with your files on RAP.

Video
UKB RAP CLI Series 5: Working With Apps Using dx run
Learn how to work and run your apps via the CLI.

Video
UKB RAP CLI Series 4: Working With Files via CLI
An overview on file management best practices and how to access and work with your files via the CLI.

Video
UKB RAP CLI Series 2: Logging In and Selecting Projects
Learn how to log into the UK Biobank Research Analysis Platform and how to access your projects via the CLI.

Video
RStudio Trial Version Now Available on the DNAnexusPowered UK Biobank Research Analysis Platform
The RStudio Trial Version is now available for UK Biobank Researchers to access on the DNAnexus-Powered UK Biobank Research Analysis Platform until August 31st. Users can now use R and RMarkdown notebooks to load and analyze data within a dedicated programming interface.

Video
Introducing the UK Biobank Research Analysis Platform
Leveraging the power and scalability of the cutting-edge, cloud-native DNAnexus Platform, the Research Analysis Platform enables researchers easily and quickly to explore and analyze the incredibly rich UK Biobank dataset

Video
Introduction to the precisionFDA Platform
A community platform for next-generation sequencing assay evaluation and regulatory science exploration.

Video
Scaling up Rapid Precision
Medicine in the NICU at
Rady Children’s Hospital
Wendy Benson, Vice President of Strategic Initiatives at Rady Children's Institute for Genomic Medicine explains how the DNAnexus Platform supports rapid genome sequencing in the NICU/PICU setting and expands their genomic pipelines to hospitals nationwide.

Webinar
Whole Genome Sequencing for Healthy Individuals
Learn how Human Longevity inc. used the DNAnexus Titan Platform on Amazon Web Services to streamline their genomics infrastructure. This enabled the company to focus on product improvements over maintenance of infrastructure.
Webinar
FASTQ to Final Report: An Ultra-Fast Workflow for Comprehensive Genomic Profiling
With a single CGP test, we can interrogate hundreds of genes, using less tissue and increasing the probability of detecting actionable findings.
Webinar
Analyzing with RStudio Trial Version: Using R and RMarkdown
RStudio Workbench Trial Version is now available on the UK Biobank Research Analysis Platform, allowing users to use RStudio in their analysis. This session covers everything you’ll need to know to start working with the application and use...
Webinar
Cloud Computing for HPC Users
Coming from high performance computing? Learn equivalent cloud-based methods for running bioinformatics jobs quickly on the Research Analysis Platform.
Webinar
How Regeneron scaled its cloud to support millions of samples a year
Learn from thought leaders from Regeneron and DNAnexus.
Webinar
Cardiovascular Researcher Roundtable: Using Large-Scale Datasets for Predicting Disease Probability
Watch the panel of expert cardiovascular disease researchers as they discuss the latest advances in their field of study. They discuss their research experience, recent advances and potential roadblocks
Webinar
Analyzing the
UK Biobank Dataset
with RStudio Workbench
Learn how to create notebooks, dashboards and incorporate Shiny apps all in the cloud on the Research Analysis Platform.
Webinar
Dementia Researcher Roundtable: Working with Large-Scale Datasets to Enable Discovery
A panel of research experts discuss the landscape of Dementia research, including the Demon Network hackathon, incorporating large-scale datasets, and the importance of cloud computing and global scientific collaboration networks.
Webinar
Image Analysis on the UK Biobank
Learn about the data formats available to start running your image analysis on the Research Analysis Platform. Ondrej Klempir, Sr. Community Engagement Scientist at DNAnexus, walks you through how to access the data, reviews basic image...
Webinar
Starting Cloud Analysis in the UK Biobank
This introductory session covers basic Cloud Computing concepts that will set you up for success on the Research Analysis Platform. Topics discuss include basic cloud computing concepts, selecting instance types, and the basics of running apps on files in your...
Webinar
Visualizing and Annotating GWAS Results on the UK Biobank Research Analysis Platform
This session details visualizing GWAS results using the Research Analysis Platform. The webinar covers interactive exploration of GWAS results using the LocusZoom App and then dives deeper into variant annotation and visualization using both R and...
Webinar
Accelerating Time to Discovery with Whole Exome Sequencing on the Research Analysis Platform
Experts from Regeneron, NVIDIA, UK Biobank & DNAnexus review the exact analysis pipeline used to quickly generate the 450,000 reference data set.
Webinar
Advanced WDL Concepts and Docker
DNAnexus Experts elaborate on the starter example from our introduction to WDL webinar and add more complexity to our WDL script. Then they introduce more syntax and discuss how to use WDL with the Docker environment.
Webinar
Introduction to WDL
DNAnexus experts take you through creating a starter WDL script and explain the basics of WDL syntax and how to use it on UKB RAP. They then compare it with native DNAnexus workflows and provide you tips on how to decide when to use WDL.
Webinar
How to Create an App/Workflow & Bring your Own Tools
DNAnexus experts give you an introduction to the applet and workflow development process by building a simple project that works on Bulk files on RAP.
Webinar
GWAS on the Research Analysis Platform Using Regenie
An introduction to running GWAS using Regenie on the Research Analysis Platform. DNAnexus experts demonstrate how to run the analysis using a diabetes phenotype on the 300k data.
Webinar
UK Biobank Data: About the Data & How to Apply for Access
Learn about the mission of the UK Biobank, the new 300k whole exome sequencing data release and how to become an approved researcher from experts at UK Biobank, Regeneron, and DNAnexus
Webinar
Data Scientist Roundtable: Bioinformatics Workflow Description and Management Systems
Ever wonder which bioinformatics workflow description and management systems you should be using? We assembled a roundtable of experts from bioinformatics workflow frameworks including CWL, WDL, and Nextflow.
Webinar
UK Biobank Research Analysis Platform Overview
An introduction to using the Research Analysis Platform to explore and analyze the uniquely rich UK Biobank dataset
Webinar
How to Run Tools Already
Learn how to run apps, applets, and workflows on the UK Biobank Research Analysis Platform.
Webinar
Exploring and Analyzing UK Biobank Data with Jupyter Notebooks
Go in-depth analyzing the uniquely rich UK Biobank dataset with Jupyter notebooks. Learn how to utilize Jupyter Notebooks and Apache Spark to explore and analyze UK Biobank’s trove of phenotypic and health record data, covering 500,000 volunteer...
Webinar
Introduction to Jupyter Notebooks on RAP
An introduction to using Jupyter Notebooks on the Research Analysis Platform, to explore and analyze the uniquely rich UK Biobank dataset.
Webinar
Data Scientist Roundtable: Variant Annotation Platforms
Hear from experts from popular variant annotation platforms, OpenCRAVAT and BioProdict, and learn pros and cons of each software platform for certain projects.
Webinar
Leveraging the Immune Repertoire for Biomarker Discovery in COVID-19 & Other Inflammatory Diseases
Ankita Das, Head of Product at MIODx, discusses methods for analyzing and interpreting TCR data in the context of biomarker discovery for inflammatory diseases.
Webinar
Harnessing the Power of the Epigenome in Personalized Medicine
Ben Busby showcases best practices for integrating epigenetic data with phenotypic data at scale to conduct powerful research studies.
Webinar

Machine Learning in Biomedical Research
Learn about leading technologies and real world examples of how machine learning is used in biomedical research including how to accelerate single cell genomic analysis using NVIDIA RAPIDS, and achieve 100x faster clustering and visualization.
Webinar
Tips & Tricks Webinar Part 2: Using WDL to Develop Locally and Scale to the Cloud
DNAnexus Principal Scientist John Didion walks through how to run WDL workflows both locally and on DNAnexus.
Webinar
Tips & Tricks Webinar Part 1: Using Docker
DNAnexus Principal Scientist John Didion walks through how to use public Docker containers as part of an application and highlights best platform practices.
Webinar
Beyond 100,000 Exomes: Insights & Lessons from Regeneron’s Large Scale Sequencing in the Cloud
How Regeneron Genetics Center (RGC) collaborates with 30 institutions to build one of the world’s most comprehensive genetics databases, pairing sequenced exomes with de-identified records of more than 120,000 people to date
Webinar
Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
Overview of the growing St. Jude Cloud datasharing platform that includes more than 5,000 whole-genome, 5,000 whole-exome and 1,200 RNA-Seq datasets from more than 5,000 pediatric cancer patients and survivors.
Webinar
Building Reference Quality Genomes with the Vertebrate Genomes Project
The VGP aims to create reference quality genome assemblies of all vertebrate species on earth. Presented in this webinar is Phase I of the project.
White Paper
Multi-Omics in the Cloud
How DNAnexus & AWS Accelerate Scientific Discoveries Featured Partner: 

Today’s genomics landscape is rapidly evolving with the accelerated adoption of multi-omics by biopharma organizations, clinical diagnostics companies, and healthcare systems.
Case Study
New
TwinStrand Biosciences: Overcoming Bioinformacs Challenges to Rapidly Scale Genomics Pipelines
Dedicated to Detecting Ultra-Rare Variants with Unparalleled Sensitivity and Specificity
TwinStrand chose DNAnexus to provide the scalable and secure cloud infrastructure it needed to support customers of its DuplexSeq™ kits.
White Paper
Build or Buy?
6Questions to Consider When Evaluating Clinical Diagnostics Informatics Solutions
NGS data analysis management systems are the backbone of your dry lab, providing vital functionality for day-to-day workings of your business delivery.
White Paper
Navigating the Odyssey of Big Genomics in Biopharma R&D
While modern-day drug discovery lacks the drama of Greek mythology, we are still faced with the odyssey of how to deliver on the promise of genomics-based precision medicine.
White Paper
Harnessing Genomic Data to Accelerate Precision Medicine
The promise of precision medicine and better patient outcomes is here, through the utilization and application of genomic data in biomarker discovery and clinical research.
White Paper
DNAnexus Security & Compliance
Learn why the FDA, top pharmaceutical companies, global diagnostic test providers, genome centers and sequencing service providers have trusted DNAnexus to support their global genomics programs.
Case Study
Partnering to Advance Clinical Genomics
Featured Partner:

Discover the Difference
Learn about our experience with Microsoft Azure in this ebook. The Microsoft Cloud empowers organizations to re-envision the way they bring together people, data, and processes that better engage patients and optimize clinical and operational effectiveness.
White Paper
10Tips to
ScaleYour Diagnostics Business &
Grow Your Test Portfolio Globally
Scale
You’ve jumped ahead of the curve, leveraging next-generation sequencing (NGS) to advance precision medicine for better patient care, and you are now experiencing an explosion of demand.
White Paper
Security, Privacy & Quality for Your Genomic Analysis
DNAnexus Platform enables researchers and clinicians to focus on their genomic analyses while complying with regulations, laws and industry expectations for security and privacy.
Case Study
How One Pharma
Company Advanced
Their Drug Discovery &
Development Process
Learn how one company chose to use DNAnexus Apollo for analysis and visualization, which provided a scalable cloud environment.
White Paper
Accelerating
Precision Medicine:
Utilizing Cloud-Based Genome Informatics
to Inform NGS Diagnosis & Treatment
The underlying infrastructure that DNAnexus provides, allows us to focus on our core competencies of R&D and patient care.
Case Study
Supporting Genomic Analysis for a Global Research Consortium
The goal of the ENCODE Project is to comprehensively catalog candidate functional and regulatory elements of the human genome, and provide a foundation for studying the genomic basis of human biology and disease.