Resource Center

Welcome to the repository for all things DNAnexus. Sort through Case Studies, Webinars, White Papers, and Videos by their associated DNAnexus product and key topics for a deeper dive into the power of our platform and expertise.

Featured

Case Study New

Standardizing portable, reproducible analysis pipelines: Pharma Experience

Learn how Eli Lilly partnered with DNAnexus and used open-source standards to tackle the changing bioinformatics landscape with on-demand compute and portable, reproducible pipelines to run in any region.
White Paper

When to Build vs.
Buy an Enterprise
Genomics Platform?

Your team members contribute the most when they’re focused on science, not when they’re spending valuable time fixing and optimizing your bioinformatics system.
White Paper

4Strategies to Accelerate Precision Drug Discovery

Large-scale omics datasets are revolutionizing how pharmaceutical companies identify targets for therapeutic development, and have become one of the main paths in accelerating precision medicine.
Case Study

Ultragenyx: Overcoming Technological Challenges to Fast-Track R&D

Advancing Rare Disease Therapeutics with DNAnexus Titan™
Ultragenyx chose to implement DNAnexus Titan™, a unified NGS analysis platform, to bring data and pipelines together in one secure environment for streamlined multi-omics data analysis.
White Paper

Build or Buy?
6Questions to Consider When Investigating NGS Informatics Solutions

A bioinformatics solution is the backbone of any successful precision medicine initiative.
Case Study

Comprehensive Genome Assemblies Made Simple

Discover the Difference
De novo genome assembly is a complex task made more challenging by high levels of genetic diversity, repetitive elements, and duplicated genomic regions.
White Paper

Working with
UK Biobank Data

A Research Guide

Do you have the right informatics strategy to get to insights quickly while working with the UK Biobank (UKB) dataset?
Case Study

Rapid Whole-Genome Sequencing Decreases Infant Morbidity and
Cost of Hospitalizationst

rWGS is a unique, high-cost healthcare innovation that appears to improve healthcare outcomes while decreasing cost of care.
Video

UKB RAP CLI Series 3: Searching for Files Using dx find

Best practices for how to sort for and find your data via the CLI on the UK Biobank Research Analysis Platform
Video

UKB RAP CLI Series 1: Introduction to Command Line Interface (CLI)

Gain an understanding of the Command Line Interface on the UK Biobank Research Analysis Platform and how you can use it to perform all of your work on the Platform.
Video

Garvan Institute Makes Genomic Medicine a Reality

Video

Large-Scale Sequencing at Regeneron Genetics Center

Jeffrey Reid, PhD, Executive Director of Genome Informatics at Regeneron presents lessons learned from largescale sequencing in the cloud with Regeneron Genetics Center.
Blog

DNAnexus Detectives: Using Amazon Web Services to Help Solve a Medical Mystery

Video

How to Use RStudio on the UK Biobank Research Analysis Platform

UK Biobank researchers can now access RStudio as a trial version on the DNAnexus-powered Research Analysis Platform. This tutorial covers how to launch RStudio Workbench, using RStudio and working with your files on RAP.
Video

UKB RAP CLI Series 5: Working With Apps Using dx run

Learn how to work and run your apps via the CLI.
Video

UKB RAP CLI Series 4: Working With Files via CLI

An overview on file management best practices and how to access and work with your files via the CLI.
Video

UKB RAP CLI Series 2: Logging In and Selecting Projects

Learn how to log into the UK Biobank Research Analysis Platform and how to access your projects via the CLI.
Video

RStudio Trial Version Now Available on the DNAnexusPowered UK Biobank Research Analysis Platform

The RStudio Trial Version is now available for UK Biobank Researchers to access on the DNAnexus-Powered UK Biobank Research Analysis Platform until August 31st. Users can now use R and RMarkdown notebooks to load and analyze data within a dedicated programming interface.
Video

Introducing the UK Biobank Research Analysis Platform

Leveraging the power and scalability of the cutting-edge, cloud-native DNAnexus Platform, the Research Analysis Platform enables researchers easily and quickly to explore and analyze the incredibly rich UK Biobank dataset
Video

Introduction to the precisionFDA Platform

A community platform for next-generation sequencing assay evaluation and regulatory science exploration.
Video

Natera & DNAnexus: Scaling Genetic Testing Globally

Video

Scaling up Rapid Precision
Medicine in the NICU at
Rady Children’s Hospital

Wendy Benson, Vice President of Strategic Initiatives at Rady Children's Institute for Genomic Medicine explains how the DNAnexus Platform supports rapid genome sequencing in the NICU/PICU setting and expands their genomic pipelines to hospitals nationwide.
Webinar

Whole Genome Sequencing for Healthy Individuals

Learn how Human Longevity inc. used the DNAnexus Titan Platform on Amazon Web Services to streamline their genomics infrastructure. This enabled the company to focus on product improvements over maintenance of infrastructure.
Webinar

FASTQ to Final Report: An Ultra-Fast Workflow for Comprehensive Genomic Profiling

With a single CGP test, we can interrogate hundreds of genes, using less tissue and increasing the probability of detecting actionable findings.
Webinar

Analyzing with RStudio Trial Version: Using R and RMarkdown

RStudio Workbench Trial Version is now available on the UK Biobank Research Analysis Platform, allowing users to use RStudio in their analysis. This session covers everything you’ll need to know to start working with the application and use...
Webinar

Cloud Computing for HPC Users

Coming from high performance computing? Learn equivalent cloud-based methods for running bioinformatics jobs quickly on the Research Analysis Platform.
Webinar

How Regeneron scaled its cloud to support millions of samples a year

Learn from thought leaders from Regeneron and DNAnexus.
Webinar

Cardiovascular Researcher Roundtable: Using Large-Scale Datasets for Predicting Disease Probability

Watch the panel of expert cardiovascular disease researchers as they discuss the latest advances in their field of study. They discuss their research experience, recent advances and potential roadblocks
Webinar

Analyzing the
UK Biobank Dataset
with RStudio Workbench

biobank-full-color-wide_2022-07-13-154730_padp
Learn how to create notebooks, dashboards and incorporate Shiny apps all in the cloud on the Research Analysis Platform.
Webinar

Dementia Researcher Roundtable: Working with Large-Scale Datasets to Enable Discovery

A panel of research experts discuss the landscape of Dementia research, including the Demon Network hackathon, incorporating large-scale datasets, and the importance of cloud computing and global scientific collaboration networks.
Webinar

Image Analysis on the UK Biobank

Learn about the data formats available to start running your image analysis on the Research Analysis Platform. Ondrej Klempir, Sr. Community Engagement Scientist at DNAnexus, walks you through how to access the data, reviews basic image...
Webinar

Starting Cloud Analysis in the UK Biobank

This introductory session covers basic Cloud Computing concepts that will set you up for success on the Research Analysis Platform. Topics discuss include basic cloud computing concepts, selecting instance types, and the basics of running apps on files in your...
Webinar

Visualizing and Annotating GWAS Results on the UK Biobank Research Analysis Platform

This session details visualizing GWAS results using the Research Analysis Platform. The webinar covers interactive exploration of GWAS results using the LocusZoom App and then dives deeper into variant annotation and visualization using both R and...
Webinar

Accelerating Time to Discovery with Whole Exome Sequencing on the Research Analysis Platform

Experts from Regeneron, NVIDIA, UK Biobank & DNAnexus review the exact analysis pipeline used to quickly generate the 450,000 reference data set.
Webinar

Advanced WDL Concepts and Docker

DNAnexus Experts elaborate on the starter example from our introduction to WDL webinar and add more complexity to our WDL script. Then they introduce more syntax and discuss how to use WDL with the Docker environment.
Webinar

Introduction to WDL

DNAnexus experts take you through creating a starter WDL script and explain the basics of WDL syntax and how to use it on UKB RAP. They then compare it with native DNAnexus workflows and provide you tips on how to decide when to use WDL.
Webinar

How to Create an App/Workflow & Bring your Own Tools

DNAnexus experts give you an introduction to the applet and workflow development process by building a simple project that works on Bulk files on RAP.
Webinar

GWAS on the Research Analysis Platform Using Regenie

An introduction to running GWAS using Regenie on the Research Analysis Platform. DNAnexus experts demonstrate how to run the analysis using a diabetes phenotype on the 300k data.
Webinar

UK Biobank Data: About the Data & How to Apply for Access

Learn about the mission of the UK Biobank, the new 300k whole exome sequencing data release and how to become an approved researcher from experts at UK Biobank, Regeneron, and DNAnexus
Webinar

Data Scientist Roundtable: Bioinformatics Workflow Description and Management Systems

Ever wonder which bioinformatics workflow description and management systems you should be using? We assembled a roundtable of experts from bioinformatics workflow frameworks including CWL, WDL, and Nextflow.
Webinar

UK Biobank Research Analysis Platform Overview

An introduction to using the Research Analysis Platform to explore and analyze the uniquely rich UK Biobank dataset
Webinar

How to Run Tools Already

Learn how to run apps, applets, and workflows on the UK Biobank Research Analysis Platform.
Webinar

Exploring and Analyzing UK Biobank Data with Jupyter Notebooks

Go in-depth analyzing the uniquely rich UK Biobank dataset with Jupyter notebooks. Learn how to utilize Jupyter Notebooks and Apache Spark to explore and analyze UK Biobank’s trove of phenotypic and health record data, covering 500,000 volunteer...
Webinar

Introduction to Jupyter Notebooks on RAP

An introduction to using Jupyter Notebooks on the Research Analysis Platform, to explore and analyze the uniquely rich UK Biobank dataset.
Webinar

Data Scientist Roundtable: Variant Annotation Platforms

Hear from experts from popular variant annotation platforms, OpenCRAVAT and BioProdict, and learn pros and cons of each software platform for certain projects.
Webinar

Leveraging the Immune Repertoire for Biomarker Discovery in COVID-19 & Other Inflammatory Diseases

Ankita Das, Head of Product at MIODx, discusses methods for analyzing and interpreting TCR data in the context of biomarker discovery for inflammatory diseases.
Webinar

Harnessing the Power of the Epigenome in Personalized Medicine

Ben Busby showcases best practices for integrating epigenetic data with phenotypic data at scale to conduct powerful research studies.
Webinar


Machine Learning in Biomedical Research

Learn about leading technologies and real world examples of how machine learning is used in biomedical research including how to accelerate single cell genomic analysis using NVIDIA RAPIDS, and achieve 100x faster clustering and visualization.
Webinar

Tips & Tricks Webinar Part 2: Using WDL to Develop Locally and Scale to the Cloud

DNAnexus Principal Scientist John Didion walks through how to run WDL workflows both locally and on DNAnexus.
Webinar

Tips & Tricks Webinar Part 1: Using Docker

DNAnexus Principal Scientist John Didion walks through how to use public Docker containers as part of an application and highlights best platform practices.
Webinar

Beyond 100,000 Exomes: Insights & Lessons from Regeneron’s Large Scale Sequencing in the Cloud

How Regeneron Genetics Center (RGC) collaborates with 30 institutions to build one of the world’s most comprehensive genetics databases, pairing sequenced exomes with de-identified records of more than 120,000 people to date
Webinar

Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud

Overview of the growing St. Jude Cloud datasharing platform that includes more than 5,000 whole-genome, 5,000 whole-exome and 1,200 RNA-Seq datasets from more than 5,000 pediatric cancer patients and survivors.
Webinar

Building Reference Quality Genomes with the Vertebrate Genomes Project

The VGP aims to create reference quality genome assemblies of all vertebrate species on earth. Presented in this webinar is Phase I of the project.
White Paper

Multi-Omics in the Cloud
How DNAnexus & AWS Accelerate Scientific Discoveries
Featured Partner:

Today’s genomics landscape is rapidly evolving with the accelerated adoption of multi-omics by biopharma organizations, clinical diagnostics companies, and healthcare systems.
Case Study New

TwinStrand Biosciences: Overcoming Bioinformacs Challenges to Rapidly Scale Genomics Pipelines

Dedicated to Detecting Ultra-Rare Variants with Unparalleled Sensitivity and Specificity
TwinStrand chose DNAnexus to provide the scalable and secure cloud infrastructure it needed to support customers of its DuplexSeq™ kits.
White Paper

Build or Buy?
6Questions to Consider When Evaluating Clinical Diagnostics Informatics Solutions

NGS data analysis management systems are the backbone of your dry lab, providing vital functionality for day-to-day workings of your business delivery.
White Paper

Navigating the Odyssey of Big Genomics in Biopharma R&D

While modern-day drug discovery lacks the drama of Greek mythology, we are still faced with the odyssey of how to deliver on the promise of genomics-based precision medicine.
White Paper

Harnessing Genomic Data to Accelerate Precision Medicine

The promise of precision medicine and better patient outcomes is here, through the utilization and application of genomic data in biomarker discovery and clinical research.
White Paper

DNAnexus Security & Compliance

Learn why the FDA, top pharmaceutical companies, global diagnostic test providers, genome centers and sequencing service providers have trusted DNAnexus to support their global genomics programs.
Case Study

Partnering to Advance Clinical Genomics

Discover the Difference
Learn about our experience with Microsoft Azure in this ebook. The Microsoft Cloud empowers organizations to re-envision the way they bring together people, data, and processes that better engage patients and optimize clinical and operational effectiveness.
White Paper

10Tips to
Scale
Your Diagnostics Business &
Grow Your Test Portfolio Globally

You’ve jumped ahead of the curve, leveraging next-generation sequencing (NGS) to advance precision medicine for better patient care, and you are now experiencing an explosion of demand.
White Paper

Security, Privacy & Quality for Your Genomic Analysis

DNAnexus Platform enables researchers and clinicians to focus on their genomic analyses while complying with regulations, laws and industry expectations for security and privacy.
Case Study

How One Pharma
Company Advanced
Their Drug Discovery &
Development Process

Learn how one company chose to use DNAnexus Apollo for analysis and visualization, which provided a scalable cloud environment.
White Paper

Accelerating
Precision Medicine:
Utilizing Cloud-Based Genome Informatics
to Inform NGS Diagnosis & Treatment

The underlying infrastructure that DNAnexus provides, allows us to focus on our core competencies of R&D and patient care.
Case Study

Supporting Genomic Analysis for a Global Research Consortium

The goal of the ENCODE Project is to comprehensively catalog candidate functional and regulatory elements of the human genome, and provide a foundation for studying the genomic basis of human biology and disease.