DNANEXUS ACCEPTABLE USE POLICY (AUP)

This Acceptable Use Policy (“AUP”) defines the permitted and prohibited uses of the DNAnexus platform, services, software, and website (collectively, the “Service”). This policy is designed to protect the security, integrity, reliability, and privacy of our ecosystem, infrastructure, and users.

Use of the Service is governed by a separate agreement entered into between the user (“User”) and DNAnexus (the “Agreement”); capitalized terms in this AUP have the meaning stated in the Agreement unless otherwise defined herein. This AUP is incorporated into the Agreement by reference.

By accessing or using the Service, you agree to comply with this AUP. Any violation may result in the immediate suspension or termination of your access to the Service.

1. Compliance with Laws and Regulations.

You may use the Service only for lawful purposes. You agree not to use the Service in any manner that violates applicable local, state, national, or international laws or regulations, including but not limited to:

• Data privacy and protection laws governing health, genetic, or personal data (e.g., HIPAA, GDPR, CCPA).
• Export control laws and regulations governing the transfer of technical data, software, or biological research materials.

1. Protection of Compute and System Resources.

To ensure equitable performance and availability for all users, you are prohibited from utilizing platform resources for unapproved or abusive processing activities. You agree not to:

• Engage in cryptocurrency mining, unauthorized large-scale artificial intelligence (AI) model training, distributed computing projects (e.g., Folding@home), or similar resource-intensive processing without explicit written authorization from DNAnexus.
• Attempt to bypass, override, or manipulate platform resource allocation, billing tracking, or compute usage limits.
• Introduce intentionally inefficient code or loops designed to degrade platform performance or exhaust system resources.

1. Promotional Credits, Free Tiers, and Sponsored Accounts.

To the extent you are granted a free trial, promotional credits, biobank accelerator packages, grant-funded wallets, or other sponsored platform access (collectively, "Promotional Tiers"), your use of such resources is subject to the following strict limitations:

• Sole Discretionary Discontinuation: Promotional Tiers and credits are provided as a discretionary commercial courtesy. DNAnexus reserves the absolute right, in its sole discretion and without liability or prior notice to you, to modify, throttle, decrease, expire, or zero out any promotional credit balances, or to terminate access to any free tier.
• "As-Is" Expiration and No Liability for Data/Compute Loss: All Promotional Tiers are provided strictly on an "AS-IS" basis. Upon the exhaustion, expiration, reduction, or discretionary termination of your promotional credits or free tier access:
• Any active, running, or queued analytical pipelines or compute clusters will be instantly terminated, regardless of execution progress or completion status.
• DNAnexus shall have no obligation to preserve, backup, or maintain any data, intermediate files, metadata, or pipeline environments stored within an account or project funded solely by expired promotional credits.
• DNAnexus expressly disclaims any and all liability for lost research progress, corrupt or incomplete datasets, disrupted pipelines, data deletion, or any direct or indirect damages resulting from credit expiration or the resulting service termination.
• No Monetary or Cash-Out Value: Promotional credits, platform vouchers, and sponsored wallets have no independent property rights, accrued financial value, or cash-equivalent value. They cannot be redeemed for cash, refunded, transferred, sold, or exchanged under any circumstances.
• Approved Projects Only: Promotional Tiers may only be used for the specific research project, evaluation, or biobank application for which they were expressly approved by DNAnexus or its partners. You are strictly prohibited from applying promotional compute or storage allocations to unrelated commercial, proprietary, or personal pipelines.
• Non-Transferability: You may not transfer, sell, pool, or assign promotional credits or sponsored project access to any other user, organization, or distinct platform account without explicit written consent from DNAnexus.
• No Automated Stacking: You are prohibited from creating multiple fictitious accounts or automated identities (Sybil attacks) to repeatedly harvest free tier computing power, sign-up credits, or initial project wallets.

1. Data Privacy and Genetic Integrity.

Given the sensitive nature of biomedical data processed on the platform, strict data boundaries must be maintained. You agree not to:

• Attempt to re-identify, de-anonymize, or pseudonymize human biological, clinical, or genomic data that has been provided as de-identified or anonymous.
• Cross-reference platform data with external data sources—including but not limited to public consumer genealogy databases, public records, or social registries—with the intent or effect of uncovering individual identities without explicit, documented legal consent.
• Upload, share, or process data for which you do not possess the required legal rights, patient consents, or institutional authorizations.

1. Third-Party Data Use Agreements and Restrictions.

If you access, download, or utilize data provided by third parties on or through the Service (including but not limited to public reference datasets, managed-access biobanks, or data shared by other platform users), you agree to strictly comply with all applicable data use agreements, licensing terms, consent frameworks, and institutional restrictions governing that data. You are solely responsible for obtaining all necessary permissions and ensuring that your analytical workflows align with the explicit boundaries set by the data owner or custodian.

1. Security, Testing, and Scraping.

You must respect the technical boundaries and security measures of the Service. Except as explicitly authorized by DNAnexus in writing, you agree not to:

• Reverse engineer, decompile, disassemble, or otherwise attempt to derive the source code, underlying architecture, or algorithms of the Service, or attempt to discover, exploit, or circumvent any technical limitation, quota, security control, or usage restriction built into the Service with the intent of bypassing it.
• Circumvent, evade, or interfere with any rate limiting, throttling, quota, or usage control imposed by DNAnexus, including by creating multiple, duplicate, or shell accounts, or by orchestrating parallel processes or sessions across accounts, in order to exceed the limits that would otherwise apply to a single account. You acknowledge that DNAnexus may apply rate limiting or throttling measures to your use of the Service at its sole discretion, and you agree to accept and comply with any such measures.
• Perform security penetration testing, vulnerability scanning, network probing, or stress/load testing against any component of the Service.
• Use automated systems, bots, scripts, or scrapers to crawl, scrape, extract, or index data, user directories, proprietary tools, or intellectual property from the platform.
• Interfere with, disrupt, or attempt to gain unauthorized access to the accounts, compute environments, storage elements, or networks of other platform users.

1. Biosecurity and Dual-Use Research.

The Service must not be used to facilitate harm or create biological or chemical threats. You agree not to use the Service, its analytics tools, or its pipeline processing capabilities for:

• The design, development, production, optimization, or weaponization of biological agents, toxins, restricted pathogens, or chemical agents.
• Any activities classified as Dual Use Research of Concern (DURC) that violate international biosecurity frameworks, export regimes, or national safety guidelines.

1. Prohibited Content and Conduct.

You agree not to upload, post, or distribute any content, or engage in any conduct on the Service that:

• Infringes upon the intellectual property, patent, trademark, or trade secret rights of DNAnexus or any third party.
• Contains, propagates, or distributes malicious code, including but not limited to malware, viruses, worms, spyware, ransomware, Trojan horses, rootkits, keyloggers, logic bombs, backdoors, exploit code, denial-of-service tools, or corrupted files, or any other code or program intended to disrupt, damage, or gain unauthorized access to systems or data.
• Is unlawful, defamatory, libelous, tortious, obscene, harassing, threatening, hateful, or incites violence.
• Involves sending unsolicited mass communications, spam, phishing attempts, or deceptive social engineering practices.
• Conducts or publishes research or analysis that lacks ethical review or approval customarily required for that research (e.g., Institutional Review Board or equivalent ethics committee approval).
• Represents, references, or implies that any research, analysis, or publication prohibited by this AUP was conducted using, validated by, or affiliated with DNAnexus or the Service, regardless of where such research was actually performed.
• Engages in phishing, pretexting, or other social engineering directed at other users of the Service, including messages, prompts, or application interfaces designed to induce a user to disclose login credentials, API keys, tokens, or other account access information.
• Induces, incentivizes, or solicits other users to install an application, grant data or account access permissions, or take any other action on the Service through misleading, coercive, or deceptive means, including for the purpose of artificially inflating application ratings, reviews, installations, or usage metrics.
• Use the Service in a manner that causes DNAnexus to become impaired in its ability to send communications on its own or on its customers’ behalf (e.g., by causing DNAnexus to become registered on any Email DNS blacklist or otherwise be denied services by any other third party communications service provider).

1. Disclaimer of Warranties Regarding Data.

DNAnexus provides the platform infrastructure and analytical tools, but does not control, vet, or validate the accuracy, completeness, quality, clinical relevance, or integrity of any data uploaded, stored, or distributed on the Service by third parties or users.

All data on the platform is provided on an "AS IS" and "AS AVAILABLE" basis. DNAnexus makes no warranties, express or implied—including any implied warranties of merchantability, fitness for a particular purpose, non-infringement, or that the data is accurate, error-free, or compliant with any specific scientific or regulatory standard. Your reliance on any data accessed through the Service is strictly at your own risk.

1. Artificial Intelligence Features and output Limitations.

Nature of the Technology: We may provide features within the Services that are powered by artificial intelligence, machine learning, or similar technologies ("AI Features"). You acknowledge that artificial intelligence is a rapidly evolving field and that the underlying technology is probabilistic and experimental in nature.

Accuracy of Output: By submitting inputs or prompts to the AI Features, you may receive generated content, text, data, or materials ("Output"). Due to the nature of AI, the Output may not always be accurate, complete, or reliable. The AI Features may occasionally generate Output that is false, misleading, out-of-date, or offensive. The Output does not represent our views or opinions.

User Responsibility and Verification: You are solely responsible for your use of the AI Features and any Output you generate. You acknowledge that you should not rely on the Output as a sole source of truth or factual information. You must independently evaluate, verify, and check the accuracy, reliability, and appropriateness of the Output for your specific use case, including utilizing human review as necessary, before relying on, using, publishing, or sharing the Output.

No Professional Advice: Output generated by the AI Features is provided for general informational purposes only. It is not intended to be, and must not be used as, a substitute for professional advice, including but not limited to medical, legal, financial, tax, or psychological advice.

Assumption of Risk: Your use of the AI Features and reliance on any Output is strictly at your own risk. To the maximum extent permitted by applicable law, we disclaim all warranties, express or implied, regarding the accuracy, reliability, or fitness of the AI Features and the Output. We shall not be liable for any dam

1. Enforcement, Investigation, and Remedies.

DNAnexus reserves the right, but does not assume the obligation, to monitor and investigate violations of this AUP. To protect the platform and the broader community, we may take immediate action without prior notice, including:

• Temporarily or permanently suspending or terminating access to the Service.
• Imposing, modifying, or removing late limits, quotas, or absolute usage limits on specific features, functions, or the Service as a whole, with or without prior notice, and without liability to you for any resulting disruption to your use of the Service.
• Accessing, reviewing, and retaining any content, data, code, communications, system logs, or other materials submitted to, generated by, or transmitted through the Service that DNAnexus reasonably believes are relevant to an actual or suspected violation of this AUP, for purposes of investigating and remedying such violations. DNAnexus may disclose such materials to law enforcement, regulators, or other third parties as DNAnexus determines is reasonably necessary to investigate or address the violation, subject to DNAnexus’s confidentiality obligations under the Agreement and applicable law.
• Removing, modifying, or blocking access to non-compliant content or data.
• Cooperating fully with law enforcement authorities, regulatory bodies, or affected third parties, which may include disclosing account information, system logs, or transaction history in accordance with applicable legal processes.